Access request submitted ✓
Private beta — now accepting researchers

AI native platform for multi-omics research

OmniBioAI unifies reproducible multi-omics analysis, agentic AI reasoning, and enterprise-grade infrastructure — across local, HPC, and cloud environments.

↗ Request Access ▶ Watch Demo
50+Pipelines
500+Integrated tools
125+Plugins
10+Agentic flows
20+Services

// Core capabilities

Built for real science,
not demos

Every component is designed with clinical-grade reliability and reproducibility at its core.

Agentic AI reasoning

LangGraph-based orchestration with RAG-powered assistants using Hugging Face and Ollama — bridging deterministic bio-computation with explainable AI interpretation.

Workflow agnostic

Native support for WDL, Nextflow, Snakemake, and CWL. Cloud-agnostic Tool Execution Service ensures 1:1 parity between local and massive-scale genomic execution.

GPU-accelerated stack

Optimized on NVIDIA PyTorch with CUDA on DGX Spark. High-performance GNNs for drug discovery and deep learning for single-cell transcriptomics.

End-to-end provenance

Production-grade Model Registry and LIMS-X metadata system for total traceability — from raw FASTQ to drug-target intelligence and pathway enrichment.

Reliability-first design

98% average test coverage across 11 microservices. Sub-3ms latency for critical service handshakes. Built for clinical-grade stability from day one.

Plugin ecosystem

Extensible plugin architecture with OnboardAI documentation browser. 30,000+ lines of living documentation updated after every commit.

Modular pipeline system

Each bioinformatics workflow is modular, allowing researchers to customize, extend, or replace analysis steps without breaking reproducibility.

Cloud & HPC ready

Runs consistently across local machines, Slurm-based HPC clusters, and cloud platforms like AWS, Azure, and GCP with identical execution logic.

🤖
Agentic workflow orchestration

LangGraph-based agentic workflows dynamically plan, execute, and adapt bioinformatics pipelines, enabling multi-step reasoning across tools, datasets, and analysis stages.


// Multi-omics coverage

Every modality,
one platform

From raw sequencing reads to biological insight — OmniBioAI covers the full spectrum of modern genomics.

scRNA-seq
Single-cell transcriptomics

QC, integration, clustering, trajectory inference, differential expression, TF network modeling, and pathway enrichment.

WGS / WES
Whole exome & genome

GATK variant calling, SnpEff annotation, SKAT-O burden testing, NMF, and decile prioritization pipelines.

Proteomics
Protein expression analysis

LEV, SEV, and plasma sample analysis with GSEA, ssGSEA, GSVA, ReactomePA enrichment and volcano plots.

Drug discovery
GNN-based target identification

Graph neural networks for drug-target interaction prediction and pathway-level disease modeling.

Clinical
Translational pipelines

Patient cohort analysis, variant burden testing, and clinical report generation for precision medicine.

ATAC-seq
Chromatin accessibility

Open chromatin profiling, peak calling, footprinting, and transcription factor binding site analysis.

ChIP-seq
Protein-DNA interactions

Histone modification and transcription factor binding analysis with peak annotation and motif enrichment.

circRNA
Circular RNA analysis

Detection, quantification, and functional annotation of circular RNAs from RNA-seq data.

RNA-seq
Bulk transcriptomics

Alignment, quantification, differential expression, and pathway analysis for bulk RNA sequencing.

Spatial
Spatial transcriptomics

Spatially resolved gene expression mapping and cell-type deconvolution across tissue sections.

Spatial single-cell
Spatial + single-cell integration

Joint analysis of spatial context and single-cell resolution for deep tissue-level insights.

SV calling
Structural variant detection

Detection and annotation of large-scale genomic rearrangements including inversions, deletions, and translocations.

Methylation
Epigenome methylation pipeline

Bisulfite sequencing → CpG calling → DMR detection → epigenetic age/biomarker analysis.

Multi-omics
Integrated multi-modal analysis

Cross-modality data integration combining genomic, transcriptomic, and epigenomic layers for systems-level insights.

CRISPR
Genome editing & screen analysis

CRISPR screen analysis including guide RNA QC, alignment, indel detection, and editing efficiency scoring.

variant_ml
Variant prioritization ML

Feature engineering + ML ranking of pathogenic variants using phenotype + genomic signals.

PythonRNextflow WDLSnakemakeCWL GATKSeuratDESeq2 LangGraphPyTorchCUDA DockerKubernetesFastAPI DjangoCeleryRedis MySQLAWSAzureGCP SlurmHuggingFaceOllama

// System requirements

What you need
to get started

OmniBioAI Studio runs on any modern Linux or macOS machine with Docker installed. One download, no command line needed.

💾
Memory

Minimum: 16 GB RAM
Recommended: 32 GB RAM
With local LLM: 64 GB RAM

💿
Storage

AppImage / DMG: ~84 MB
Docker images: ~5 GB (one-time pull)
Data + work dirs: 50–200 GB

🖥️
Operating System

Linux: Ubuntu 20.04+ (AppImage)
macOS: 12+ Apple Silicon + Intel
Windows: WSL2 + Docker

🐳
Docker

Docker Engine 24+ or Docker Desktop
Docker Compose v2 (included)
No other dependencies required

GPU (Optional)

NVIDIA GPU + nvidia-container-toolkit
Required only for local LLM inference
Cloud API (Claude/GPT) works without

🌐
Network

Internet required for first boot only
~10 GB pulled from ghcr.io automatically
Fully offline after first run

● Private Beta · v0.2.0-beta

Access requires approval

Approved researchers receive a platform-specific download link and onboarding support within 1–2 business days.

↗ Request Beta Access

License key included · 30-day free trial


// Downloads

OmniBioAI Studio
v0.2.0-beta

Choose your platform and architecture. All installers include a 30-day free trial license.

macOS
🍎
Apple Silicon

M1 / M2 / M3 / M4
Native ARM64 build

↓ DMG · 84 MB
💻
Intel Architecture

Legacy Intel Mac
Native x86_64 build

↓ DMG · 86 MB
🐧 Linux x86_64 (Intel / AMD)
📦
AppImage

Any Linux distro
Ubuntu 20.04+

↓ AppImage · 84 MB
📦
DEB Package

Ubuntu / Debian / Mint
amd64

↓ DEB · ~85 MB
sudo dpkg -i omnibioai_*.deb
📦
RPM Package

RHEL / Fedora / CentOS
x86_64

↓ RPM · ~85 MB
sudo rpm -i omnibioai-*.rpm
🦾 Linux ARM64 (DGX / Graviton / Raspberry Pi)
📦
AppImage ARM64

Any ARM64 Linux
aarch64

↓ AppImage · ~80 MB
chmod +x *.AppImage && ./OmniBioAI*.AppImage
📦
DEB ARM64

Ubuntu / Debian ARM64
aarch64

↓ DEB · ~85 MB
sudo dpkg -i omnibioai_*arm64.deb
📦
RPM ARM64

RHEL / Fedora ARM64
aarch64

↓ RPM · ~85 MB
sudo rpm -i omnibioai-*.aarch64.rpm
🪟 Windows (WSL2)
🪟
Windows Installer

Windows 10 / 11 x64
Requires WSL2 Enabled

Join Waitlist →
Available June 1, 2026

// System architecture

Clinical-grade design

A containerized, microservices-led environment built for massive scale, traceability, and high performance.

Engineered for absolute provenance

OmniBioAI Studio separates user experience orchestration from heavy-lifting workflow engines. It executes multi-omics routines natively, passing biological insights directly into automated reporting and visualization pipelines.

With strict isolation across its core service layers, researchers can safely deploy pipelines locally or easily burst to Slurm or cloud systems without code modifications.

OmniBioAI Studio UI (Desktop Frontend)
│ Handshake (sub-3ms latency)
Agentic AI Orchestration (LangGraph / Ollama / HF)
│ Orchestration & data mapping
BioFlow Runtime Engine (Nextflow / WDL / Snakemake)
│ Tracking & provenance link
LIMS-X Metadata & Sample Tracking System
│ Infrastructure layer
GPU Accelerated Stack (CUDA / NVIDIA DGX Spark)

// Academic presence

Peer-reviewed research

Methods developed and powered by OmniBioAI platform architectures across transcriptomics and proteomics.

2025
Genetic mutations in lymphocytic variant of hypereosinophilic syndrome: study of five siblings
Frontiers in Medicine · December 2025
↗ View paper
2018
Whole Exome Sequencing identifies common and rare variant Metabolic QTLs in a Middle Eastern Population
Nature Communications · January 2018
↗ View paper
2015
MetaRNA-Seq: An Interactive Tool to Browse and Annotate Metadata from RNA-Seq Studies
BioMed Research International · August 2015
↗ View paper

// Apply for private beta

Request Access

Get access to OmniBioAI Studio v0.2.0-beta. Accelerate your multi-omics data integration with robust, explainable AI workflows.

🐧 Linux Ubuntu / Debian / RHEL AppImage · 78 MB
🍎 macOS Apple Silicon or Intel DMG · 84 MB
🪟 Windows WSL2 required EXE · Coming soon